季丙元

发布者:精神卫生学院发布时间:2019-06-19浏览次数:137


季丙元,神经生物学博士,副教授;中国神经学会会员中国细胞生物学会会员山东神经学会会员、美国细胞生物学会会员。主要研究方向为G蛋白偶联受体的二聚化及其相互作用机制研究、GPCR及其同源或异源二聚体在抑郁症和阿尔茨海默病中的发病机制及临床转化研究。主讲课程:本科生《医学细胞生物学》、《医学遗传学》及留学生课程《cell biology》。主持或参与国家自然科学基金、省自然科学基金3项;发表SCI论文14篇,其中第一作者或通讯作者6篇;参编教材4部。


  代表性学术论文(2012年至今)

1. Ji B, Liu H, Zhang R, Jiang Y, Wang C, Li S, Chen J, Bai B: Novel signaling of dynorphin at kappa-opioid receptor/bradykinin B2 receptor heterodimers. Cellular signalling 2017, 31:66-78.

2. Ji B, Cheng B, Pan Y, Wang C, Chen J, Bai B: Neuroprotection of bradykinin/bradykinin B2 receptor system in cerebral ischemia. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017, 94:1057-1063.

3. Li W, Li G, Ji B#, Zhang Q, Qiu J: Neuroanatomical Correlates of Creativity: Evidence From Voxel-Based Morphometry. Frontiers in psychology 2019, 10:155.

4. Liu Y, Zhang N, Bao G, Huang Y, Ji B#, Wu Y, Liu C, Li G: Predictors of depressive symptoms in college students: A systematic review and meta-analysis of cohort studies. Journal of affective disorders 2019, 244:196-208.

5. Kong Q, Hao Y, Li X, Wang X, Ji B*, Wu Y: HDAC4 in ischemic stroke: mechanisms and therapeutic potential. Clinical epigenetics 2018, 10(1):117.

6. Wang Q, Wang C, Ji B, Zhou J, Yang C, Chen J: Hapln2 in Neurological Diseases and Its Potential as Therapeutic Target. Frontiers in aging neuroscience 2019, 11:60.

7. Xue Q, Bai B, Ji B, Chen X, Wang C, Wang P, Yang C, Zhang R, Jiang Y, Pan Y et al: Ghrelin Through GHSR1a and OX1R Heterodimers Reveals a Galphas-cAMP-cAMP Response Element Binding Protein Signaling Pathway in Vitro. Frontiers in molecular neuroscience 2018, 11:245.

8. Wang C, Wang Q, Ji B, Pan Y, Xu C, Cheng B, Bai B, Chen J: The Orexin/Receptor System: Molecular Mechanism and Therapeutic Potential for Neurological Diseases. Frontiers in molecular neuroscience 2018, 11:220.

9. Jiang Y, Liu H, Ji B, Wang Z, Wang C, Yang C, Pan Y, Chen J, Cheng B, Bai B: Apelin13 attenuates ER stressassociated apoptosis induced by MPP+ in SHSY5Y cells. International journal of molecular medicine 2018, 42(3):1732-1740.

10. Xue Q, Li X, Yang C, Ji B, Li Y, Yan Y, Yang X, Wang C, Chen T: Efficacy of recombinant adenovirus expressing a fusion gene from GM-CSF and Epstein-Barr virus LMP2A in a mouse tumor model. Human vaccines & immunotherapeutics 2017, 13(10):2260-2268.

11. Liu H, Tian Y, Ji B, Lu H, Xin Q, Jiang Y, Ding L, Zhang J, Chen J, Bai B: Heterodimerization of the kappa opioid receptor and neurotensin receptor 1 contributes to a novel beta-arrestin-2-biased pathway. Biochimica et biophysica acta 2016, 1863(11):2719-2738.

12. Wang C, Ji B, Cheng B, Chen J, Bai B: Neuroprotection of microRNA in neurological disorders (Review). Biomedical reports 2014, 2(5):611-619.

13. Cheng B, Guo Y, Li C, Ji B, Pan Y, Chen J, Bai B: Edaravone protected PC12 cells against MPP(+)-cytoxicity via inhibiting oxidative stress and up-regulating heme oxygenase-1 expression. Journal of the neurological sciences 2014, 343(1-2):115-119.

14. Xin Q, Ji B, Cheng B, Wang C, Liu H, Chen X, Chen J, Bai B: Endoplasmic reticulum stress in cerebral ischemia. Neurochemistry international 2014, 68:18-27.